Laboratory of Molecular Biophysics Graduate Student Opportunities.

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Light dependent processes in Photoreceptors and Photoactive Proteins

• Phytochrome and Cryptochrome photoreceptors
• Photochemistry of Green Fluorescent Protein

Selected references.

van Thor JJ, Georgiev GY, Towrie M, Sage JT. Ultrafast and low barrier motions in the photoreactions of the green fluorescent protein. J Biol Chem. 2005 Sep 30;280(39):33652-9.

Kennis JT, Larsen DS, van Stokkum IH, Vengris M, van Thor JJ, van Grondelle R. Uncovering the hidden ground state of green fluorescent protein. Proc Natl Acad Sci U S A. 2004 Dec 28;101(52):17988-93.

van Thor JJ, Hellingwerf KJ. Fluorescence resonance energy transfer (FRET) applications using green fluorescent protein. Energy transfer to the endogenous chromophores of phycobilisome light-harvesting complexes. Methods Mol Biol. 2002;183:101-19.

Hendriks J, Gensch T, Hviid L, van Der Horst MA, Hellingwerf KJ, van Thor JJ. Transient exposure of hydrophobic surface in the photoactive yellow protein monitored with Nile Red. Biophys J. 2002 Mar;82(3):1632-43.

van Thor, J.J., Gensch, T., Hellingwerf, K.J. and Johnson, L.N.(2002) Phototransformation of green fluorescent protein with UV and visible light leads to decarboxylation of glutamate 222. Nature Struct. Biol. 9, 37-41